Biologyhard · Past Paper

Which of the following describes a frame-shift mutation?

AReplacement of one base with another
BInsertion or deletion of one or more nucleotides
CLoss of an entire chromosome
DInversion of a DNA segment

✓ Correct Answer: BInsertion or deletion of one or more nucleotides

Frame-shift mutations occur when nucleotides are inserted or deleted, changing the reading frame of the genetic message.

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